Awendaw was named by the Sewee Native American tribe. It is also home to an oyster shell mound created by the Sewee Tribe. It is often referred to as "The Spanish Fort". Most of the mound is still intact. The rest of it was destroyed to construct roads and homes for the citizens of Awendaw. In 1992, the town of Awendaw was first incorporated and elected its first mayor, Willam H. Alston.